A 3 years old, 1.8 kg weight, male Persian cat was presented to Firat University Animal Hospital with a history of 2 week duration polyuria, polydipsia, severe weight loss and vomiting.
Mild depression, severe weight loss, moderate dehydration, low body temperature (36.5 °C), elevated heart rate (164 beat/min), normal respiratory rate (32 breath/min), halitosis, ulcerative areas on the tongue and gingivitis was detected in the clinical examination. Left kidney was enlarged and irregular structure was detected at palpation.
The blood was taken from vena cephalica antebrachii for hematological, blood gas and serum biochemical analysis. Hematological examination of blood was performed with a fully automated blood analyzer (Prokan PE-6800 Vet, China). Blood gas analysis were performed with venous blood gas analysing system (Abl-80, Radiometer Medical ApS, Denmark). Biochemical analysis were performed in Firat University Hospital Central Laboratory with automated biochemical analysing system (Advia Centaur, Siemens, Germany).Hematological, blood gas and electrolyte analysis revealed leukocystosis, normocytic normochromic anemia, acidemia, hypernatremi and high anion gap (Table 1). Serum biochemical analysis revealed hypoproteinemia, hypoalbuminemia, hyperphosphatemia, severe uremia and severe creatinaemia (Table 2).
Sterile urinary catheter (Buster Cat Catheters, Kruuse, Denmark) was administrated to collecting urine sample. Urine spesific gravity was determined with brix refractometer (ATAGO, Japan). Decreased urine specific gravity (spesific gravity: 1010) and proteinuria was detected in urinalysis with urinary test strip (Krulab Test Strip for Urine, Kruuse, Denmark).
The cat underwent abdominal ultrasonographic examination with micro convex transducer (GE 8C-RS, LOGIQ Book XP Vet, General Electric). Anechoic, round and distinct border structures was detected in the both kidneys (Figure 1).
The final diagnosis of cat was stage 4 chronic renal failure associated with PKD. The stage of chronic renal failure was evaluated as stage 4 according to International Renal Interst Society (IRIS) classification system.
The treatment was initiated with 250 mL 0.9% NaCl solution and vitamin complex (3 mL/day p.o, Supravit, Bayer). Additionally, dietary supplementsfor supporting renal function (1 g/5 kg twice a day, Ipakitine, Novakim, Turkey) and prescription diet that contains low phosphorus and sodium was recommended. But the cat died after two weeks. The necropsy was not performed beacuse of cat’s owner didn’t allow.
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