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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
2021, Cilt 35, Sayı 2, Sayfa(lar) 092-096
[ Turkish ] [ Tam Metin ] [ PDF ]
Evaluation of Deep Gray Matter by Diffusion-Weighted Imaging in Children with Tuberous Sclerosis Complex
Yeşim EROĞLU, Mustafa KOÇ
Firat University, Faculty of Medicine, Department of Radiology, Elazig, TURKIYE
Keywords: Tuberous sclerosis complex, diffusion-weighted imaging, apparent diffusion coefficient, child

Objective: The aim of this study is to compare diffusion-weighted magnetic resonance imaging values of deep gray matter structures in children diagnosed with tuberous sclerosis complex with a control group.

Materials and Methods: Between January 2015 and December 2020, 14 pediatric patients (8 boys, 6 girls; mean age 9.50±4.16) diagnosed with tuberous sclerosis complex who underwent diffusion-weighted magnetic resonance imaging, and 28 age and sex-matched control patients were retrospectively analyzed. Apparent diffusion coefficient values were measured by placing symmetric circular region of interest on bilateral thalamus and basal ganglia.

Results: A significant increase was found in the apparent diffusion coefficient values in the bilateral nucleus caudate compared to the control group in patients diagnosed with tuberous sclerosis complex (P<0.001).

Conclusion: Affecting possible deep gray matter structures in these patients may explain the physiopathology for current clinical findings and neurological disorders that may develop.


[ Turkish ] [ Tam Metin ] [ PDF ]
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