Objective: Studies of young women, including dual X-ray absorptiometry (DXA) are limited in terms of identifying when and where osteopenia starts and the degree of correlation in the T-scores as reproductive women transition into menopausal status. The aim of this study is to evaluate the values of the lowest T-score in the femoral neck, trochanter, and lumbar spine at different age ranges and the correlation with an increase in age by using DXA.

Materials and Methods: In this retrospective cohort study, DXA results of patients between the ages of 45 and 80, who were admitted to the Department of Gynecology and Obstetrics of İstanbul Teaching and Research Hospital were evaluated. The bone mineral density (BMD) measurements were performed in the anterior-posterior direction.

Results: There was a statistically significant difference observed between the T-scores of different skeletal sites between 4 groups of patients (p<0.005), except for lumbar vertebrae (p=0.02). In all age groups, the lumbar region T-score was the lowest. BMD measurements of lumbar vertebrae among the 4 age groups were unaffected by an increase in age, progressive decline in BMD occurs in the femoral neck and trochanter region with an increase in age.

Conclusion: We suggest that the lumbar BMD should be checked first in all age groups as the lumbar region was most susceptible to osteopenia. We also suggest that clinicians should pay attention to a progressive decrease in BMD density with age in the femur neck and trochanter regions and physicians to consider that lumbar vertebra BMD starts to decrease at younger ages.