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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
2022, Cilt 36, Sayı 1, Sayfa(lar) 031-034
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Investigation of Serum Uric Acid Levels in Vitamin D Deficiency
Akif DOĞANTEKİN
Özel Emek Hastanesi, İç Hastalıkları Kliniği, Gaziantep, TÜRKİYE
Keywords: Uric acid, 25-hydroxyvitamin D3, parathyroid hormone

Objective: In this study, it was aimed to investigate the relationship between vitamin D deficiency, which has many important metabolic features and is a chronic disease risk factor, and hyperuricemia.

Materials and Methods: 114 patients between the ages of 18-64 who applied to Private Gaziantep Emek Hospital were included in the study. Serum uric acid, parathyroid hormone (PTH), fasting blood glucose (FBC), hemoglobin A1c (HbA1c), urea, creatinine and 25 hydroxyvitamin D levels were studied in the blood taken from the subjects after 8-12 hours of fasting. Patients' 25-hydroxyvitamin D3 [25(OH)D3] levels are categorized as follows: ≥ 30 ng/mL adequate level (Group-1), 20-29.9 ng/mL vitamin D insufficiency (Group-2), ≤19.9 ng/mL vitamin D deficiency (Group-3). Serum uric acid levels of these 3 groups were compared.

Results: When the 3 groups were compared using One-Way ANOVA analysis, no significant difference was found between serum uric acid levels (p=0.761). The mean serum uric acid values of the groups were found to be (4.87±1.26) for group-1, (5.04±1.50) for group-2 and (4.83±1.11 for group-3).

Conclusion: It was concluded that there was no significant difference between the serum uric acid levels of the groups, and it would be beneficial to conduct prospective studies with a higher number of participants to confirm the relationship between vitamin D and serum uric acid levels, which were proven to use common metabolic pathways.


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