Objective: The main objective of this study is to assess the interest in commonly abused and co-consumed illegal drugs, ecstasy and marijuana (also known as 3,4-methylenedioxymethamphetamine (MDMA) and tetrahydrocannabinol (THC), respectively), utilizing google trends data. The primary goal of this study is to assess the interest in commonly abused and co-consumed illegal drugs, ecstasy and marijuana (also known as 3,4-methylenedioxymethamphetamine (MDMA) and tetrahydrocannabinol (THC), respectively), utilizing google trends data.

Materials and Methods: A retrospective analysis was conducted based on google trends between 2004 and 2021, utilizing the keywords ecstasy and marijuana in Turkiye (T) and world (W). Relative Search Volumes (RSV) were assessed using the GraphPad statistical method.

Results: During the period of 2007-2021, the increasing trend in interest for ecstasy (T) and marijuana (W) persisted and was statistically significant (*p<0.05). However, the interest in marijuana (T) and ecstasy (W) statistically decreased in the third five-years period compared to the second five-years period (*p<0.05). Additionally, a positive linear relationship for these drugs was observed both in T and W (r=0.2232; p<0.001 and r=0.4609; p<0.0001, respectively).

Conclusion: In utilizing this technology, insights can be drawn to prevent and address the worldwide public health issue of drug demand, supply, and addiction.