Objective: This study has been conducted to determine postpartum depression knowledge and attitudes of nurses and midwives employed in primary health care centers.

Materials and Methods: The study was carried out as cross-sectional. Samples consisted of a total of 136 nurses and midwives employed in primary health care centers located in Uskudar and Kadikoy districts of Istanbul. The survey questionnaires were prepared by the researchers according to current literature and were including a “Personal Information Form” and a “Postpartum Depression Knowledge and Opinions Form”.

Results: 16.2% of the nurses and midwives have performed postpartum depression screening and 22.8% have met a case related to postpartum depression. It has been detected that postpartum depression knowledge score average of nurses and midwives is 34.89 out of the maximum of 45 points. It has been found out that the participants had positive opinions about postpartum depression as well as the roles of nurses and midwives on postpartum depression.

Conclusions: As revealed by research results, nurses and midwives employed in primary health care centers have good levels of postpartum depression knowledge and positive attitudes, but on the other hand, this awareness is not affecting their practice sufficiently.