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Fırat University Medical Journal of Health Sciences
2020, Cilt 34, Sayı 3, Sayfa(lar) 255-264
[ Turkish ] [ Tam Metin ] [ PDF ]
The Effect of Preoperative Hematological Parameters on Mortality and Morbidity in Patients with a History of Bypass Surgery
İbrahim Burak ŞEKER1, Sadiye DENİZ ÖZSOY1, İsmail KOŞAR1, Ayhan UYSAL2, Mehmet Ali YEŞİLTAŞ1, İsmail HABERAL1,
1İstanbul Üniversitesi, Cerrahpaşa Kardiyoloji Enstitüsü, Kalp Damar Cerrahisi Anabilim Dalı, İstanbul, TÜRKİYE
2Fırat Üniversitesi, Tıp Fakültesi, Kalp Damar Cerrahisi Anabilim Dalı, İstanbul, TÜRKİYE
Keywords: N/L ratio, RDW, thrombocyte, CABG

Objective: The aim of this study was to investigate the relationship between preoperative hematologic parameters such as neutrophil/lymphocyte ratio (N/L), erythrocyte distribution width (RDW) and differences in preoperative and postoperative platelet values in patients underwent coronary artery bypass surgery (CABG) and postoperative mortality, morbidity and other reasons that prolong hospital stay.

Materials and Methods: This study included retrospective screening of post-surgical hospital records of 670 patients who underwent coronary artery bypass graft surgery under elective conditions due to ischemic heart disease without additional cardiac disease but no other surgeries.

Results: A total of 670 cases (female=151 (22.5%) and male=519 of (77.5%)) were included in the study. After CABG, Atrial Fibrillation (AF) was observed in 2.5%, Major Adverse Cardio-Cerebral Effects (MACCE) in 6.7%, and mortality rate was 4.6%. Preoperative high N/L ratio was found to be associated with AF developing after CABG and adverse effects (P<0.001 and P=0.001). Preoperative high RDW value was found to be associated with AF developing after CABG (P=0.005). The difference between postoperative and preoperative platelet counts was found to be associated with mortality after CABG (P<0.001). It was observed that the risk of mortality decreased by 3% when the platelet values increased by 1 unit (103 mm3) on the postoperative 7th day compared to the preoperative platelet values (P<0.001).

Conclusion: More detailed evaluation of preoperative hematological parameters contributes to the prediction of mortality and morbidity. With extensive studies to be done, these parameters can be included in risk scoring systems and increase the reliability of these.


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