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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
2022, Cilt 36, Sayı 2, Sayfa(lar) 101-108
[ Turkish ] [ Tam Metin ] [ PDF ]
The Relationship between Malnutrition, Inflammation and Atherosclerosis Components in Hemodialysis Patients
1Malatya Training and Research Hospital, Department of Nutrition and Dietetics, Malatya, TÜRKİYE
2Gazi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Ankara, TÜRKİYE
3Ataturk University, Faculty of Medicine, Department of Radiology, Erzurum, TÜRKİYE
Keywords: Malnutrition, inflammation, atherosclerosis, nutrition, hemodialysis

Objective: This study aimed to investigate the relationship between malnutrition, inflammation and atherosclerosis components in hemodialysis patientswith end-stage renal failure.

Materials and Methods: The study was carried out in 49 volunteer hemodialysis patients in 18-65 years with end-stage renal failure. Anthropometric measurements of the patients [(body weight (kg), height (cm), waist circumference (cm), hip circumference (cm)] and body composition analysis were performed by the researcher, and malnutrition inflammation score (MIS) questionnaire was applied. Serum C-reactive protein (CRP) levels were recorded and carotid intima-media thickness (CIMT) was measured.

Results: The median age of the patients was 49 years. Median CIMT was 0.6, median MIS was 11, CRP level was 0.6 mg/dL. There was a significant negative correlation between patients' body weight, body mass index (BMI), waist circumference, hip circumference, waist-height ratio, total body fat, lean body mass values and MIS (p<0.05). There was a positive significant correlation between age, BMI, waist circumference, hip circumference, percentage of total body fat and CIMT (p<0.05).

Conclusion: In this study, while a significant relationship was not observed between the MIS and CRP and CIMT of patients, a significant relationship was found with some anthropometric measurement and body composition parameters that may be the indicator of malnutrition. Since the relationship between malnutrition and inflammation poses a risk for atherosclerosis in hemodialysis patients, this patient group should be evaluated in terms of malnutrition and preventive measures should be taken.

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