Objective: We aimed to evaluate the clinical signs, microbiological profile, echocardiographic findings, and management strategies of infective endocarditis (IE) patients treated in our center and thus to contribute to the literature of the country.

Materials and Methods: Patients with a diagnosis of infective endocarditis diagnosed in our hospital between January 2018 and October 2022 according to the modified Duke criteria were included in the study. Patient data, clinical and laboratory findings, blood culture results, and echocardiographic findings were obtained by retrospectively scanning the hospital electronic record system.

Results: Fourteen cases, eight (57.1%) male, were included in the study. Five (35.7%) patients had artificial valve disease and four (28.5%) patients had rheumatic valve disease. The most common findings were fever (92.8%) and heart murmur (85.7%). Five (35.7%) patients had embolic complications. Microorganism growth was detected in the blood cultures of nine (64.2%) patients. Transthoracic echocardiography was performed in all patients. Transesophageal echocardiography was performed in nine (64.2%) patients. Antibacterial therapy was given to all patients. The mean duration of the treatment was 34.5±24.2 days. Only three (21.4%) patients underwent simultaneous surgical intervention. Three (21.4%) patients died.

Conclusion: Infective endocarditis is a serious disease that requires a multidisciplinary approach and has a high morbidity and mortality rate. Therefore, the management of the disease may differ from center to center. In this study, data belonging to our center are presented. However, there is a continuing need for large-scale, prospective studies on IE to contribute more to the country's literature.