It is known that aerobic exercise causes oxidative stress. Lipid peroxidation (LP), which poliunsaturate fatty acid oxidation in biological membrane, is one of the criteria of increasing oxidative stress. LP causes membrane and cell defects. Malondialdehyde (MDA) is one of the last productions of LP. The purpose of this study was to aimed to examine the effects of short term incremental exercise test, which include aerobic and anaerobic exercises, on vitamins A,E,C and MDA levels on obese patients

Total of 37 obese (BMI: 39.06±0.9 kg/m2) performed an incremental exercise test. Blood samples were taken at rest and at the maximal exercise performance. HPLC was used to determine MDA and vitamin levels.

Maximal exercise capacity was 90.2±5. Vitamin A [0.76±0.09 µg/ml vs 0.67±0.1µg/ml (P>0.05)], Vitamin E [6.09±0.4 µg/ml vs 5.78±0.4µg/ml, P>0.05] and Vitamin C [13.57±0.7µg/ml vs 14.41±0.9 µg/ml (P>0.05) ] levels did not change significantly at maximal exercise compared to basal values. However, MDA level increased significantly: 2.28±0.1 nmol/ml vs 2.71±0.1 nmol/ml (p<0.05).

Consequently, short term incremental exercise causes increase in MDA levels without altering Vitamins A, E, C levels