Objective: Infection with Toxoplasma gondii and rubella in early pregnancies causes congenital anomalies in the fetus and newborn. When susceptible pregnancies are exposed to these agents, congenital defects are formed and almost all the organs and systems of the fetus are affected. The aim of this study is to determine the seroprevalence of Toxoplasma gondii and rubella infection by pregnant women in our region and to contribute to the management of these infections in antenatal follow-up of pregnant women.

Materials and Methods: In this study Toxoplasma gondii, Rubella IgM and IgG results of pregnant women between 18 and 45 years of age in the 20th week and below, analysed by the Microbiology laboratory of Tokat Gaziosmanpasa University, Medicine Faculty Hospital between January 2016 and December 2017 are evaluated retrospectively. A total of 274 pregnancies for Toxoplasma gondii IgG and IgM antibodies, 237 for Rubella IgG and 274 for Rubella IgM antibodies were included in the study. Rubella antibodies and Toxoplasma gondii antibodies in serum samples were studied by enzyme immunoassay (EIA).

Results: The mean age of the pregnant women in the 20th gestational week and below included in the study was 29.9±0.1 years. Rubella IgM and IgG antibodies were detected in 2 (0.7%) and 233 serum samples (98.3%) respectively. Toxoplasma gondii IgM and IgG antibodies were detected in 8 (2.9%) and 65 serum samples (23.7%) respectively.

Conclusion: In this study, it was thought that the screening test would not make a significant contribution because of the Rubella IgM antibodies seropositivity is low and the rubella is also present in the national immunization schedule. However, the low seropositivity of Toxoplasma gondii IgG antibodies suggests that more attention should be shown on this infection during pregnancy. Therefore, it is believed that providing education and screening of pregnant women and woman planning pregnancy are important in preventing congenital toxoplasmosis.