Objective: It was aimed to examine the clinical results of intra-articular steroid and hyaluronic acid injection treatment in patients with gonarthrosis and requiring surgery.

Materials and Methods: Between March 11, 2020 and September 1, 2020, those who came to the orthopedics clinic with knee pain, were diagnosed with stage 3 and stage 4 gonarthrosis according to the Kellgren-Lawrence classification in the X-rays, were recommended surgery and avoided the operation for any reason (presence of pandemic, fear of surgery...) A total of 247 patients who were treated with intra-articular injection (steroid, hyaluronic acid or combined) were analyzed retrospectively. WOMAC OA index was evaluated in terms of pain, stiffness and physical function before the procedure, at the 1st week after the procedure, at the 3rd month after the procedure and at the 6th month after the procedure.

Results: WOMAC pain score reduction at 3rd month and 6th month after treatment in the combined group was significantly higher (p<0.05) than in the steroid and hyaluronate group. In the combined group, the decrease in WOMAC stiffness and functional score was significantly higher (p<0.05) at week 1, 3 months after treatment, and 6 months after treatment than in the steroid and hyaluronate group.

Conclusion: The combined use of Hyaluronic acid (HA) and Corticosteroid (CS) was generally better than HA in terms of pain control, knee function and range of motion at 3 and 6 months after injection. The use of CS alone has shown a short-term effect.