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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
2021, Cilt 35, Sayı 1, Sayfa(lar) 035-039
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Can the Triglyceride/HDL Ratio in Chronic Kidney Disease be Predictive of Cardiac Risk?
Ahmet AKTAŞ1, Mustafa Asım GEDİKLİ1, Canan KARA1, Muhammed Raşid BAKIR2
1Cumhuriyet University, Faculty of Medicine, Internal Medicine Department, Sivas, TURKIYE
2Bozok University, Research and Application Center, Yozgat, TURKIYE
Keywords: Chronic renal failure, trigliserid/HDL cholesterol ratio, cardiac risk

Objective: Chronic Kidney Failure is one of the important causes of increased morbidity and mortality recently. Cardiovascular mortality is an important cause of mortality in patients with chronic kidney failure. It has been reported that triglyceride/high density lipoprotein ratio (TG/HDL) cholesterol ratio shows cardiac risk in previous studies. In our study, we aimed to show whether there is a relationship between TG/HDL cholesterol ratio and cardiovascular risk in patients with chronic renal failure receiving dialysis treatment and not.

Materials and Methods: A single-center retrospective study. In our study, 40 healthy, 50 dialysed patients with chronic renal failure and 50 patients without receiving dialysis (predialysis) who applied to internal medicine outpatient clinic were included. Patients' files were scanned retrospectively. TG/HDL ratios were recorded and calculated.

Patients who use lipid-lowering drugs and patients with diabetes were not included in our study.

Results: TG/HDL cholesterol ratio was found to be statistically significantly higher in predialysis patients and patients receiving dialysis due to chronic renal failure compared to healthy controls. TG/HDL cholesterol ratio was higher in patients with chronic renal failure that did not undergo dialysis compared to patients with chronic renal failure that were dialysed, but it was not statistically significant.

Conclusion: As an indicator of cardiovascular mortality due to chronic kidney disease, the TG/HDL-C ratio can be an inexpensive, reproducible predictor. TG/HDL-C ratio was found to be higher in patients with chronic kidney disease that did not undergo dialysis, compared to chronic kidney patients undergoing dialysis and the healthy control group.


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